Vitamin B12 Methylcobalamin
Vitamin B12 Methylcobalamin from Greatlife is a high-quality form of Vitamin B12, specifically in the biologically active and easily absorbed methylcobalamin form. This active form of B12 ensures effective absorption and is readily available to the body. Vitamin B12 Methylcobalamin contributes to normal energy metabolism, proper nervous system function, and reduced fatigue and exhaustion. This supplement is pure, free from additives, toxins, and GMOs.
- Vitamin B12 in its active form, methylcobalamin
- Helps to reduce fatigue and exhaustion.
- Free from dairy, soy, sugar, gluten, and GMOs
- Free from artificial sweeteners, colourings, preservatives, hydrogenated oils, corn syrup, and magnesium stearate
- Dark glass jar free from BPA, phthalates, and other hormone-disrupting substances
- Manufactured under HACCP in the EU
- Suitable for vegans and vegetarians
- Buy now, pay later
- Ship all over Europe
- In stock
Vitamin B12 Methylcobalamin
Vitamin B12 Methylcobalamin from Greatlife is a potent supplement that supports energy metabolism, nervous system health, and the formation of red blood cells. Methylcobalamin, the active and easily absorbed form of Vitamin B12, plays a crucial role in the body’s metabolism and is essential for normal cell division and DNA synthesis. This form of B12 is particularly important for individuals with a reduced ability to convert cyanocobalamin into the active form.
Vitamin B12 Methylcobalamin also supports brain function and can help reduce fatigue and exhaustion by promoting normal energy metabolism. Additionally, it is important for maintaining a healthy homocysteine metabolism, which plays a significant role in cardiovascular health. As B12 is a water-soluble vitamin stored in the liver, it may be crucial to supplement it through diet or supplements, especially for vegans and older individuals with reduced absorption ability.
Studies have shown that methylcobalamin is a more effective form of B12 than cyanocobalamin, as it is directly biologically available and does not need to be converted in the body.
Vitamin B12 and the MTHFR Gene
The MTHFR gene (Methylenetetrahydrofolate reductase) is vital for the body’s conversion of folate and homocysteine metabolism. Individuals with variations in the MTHFR gene may have difficulty metabolising folate and converting B12 to its active form, which can lead to the accumulation of homocysteine in the blood – a factor linked to cardiovascular diseases and neurological issues. Methylcobalamin is particularly beneficial for individuals with MTHFR variations because it is already in its active form and can directly contribute to normal homocysteine metabolism and support nervous system function.
Vitamin B12 is an essential vitamin for everyone, but deficiency is especially common among vegans, the elderly, and individuals with reduced gastrointestinal function. A supplement with methylcobalamin ensures that the body receives the active form of B12, which it can immediately use to support energy, brain function, and blood formation.
Top-Quality Vitamin B12 Methylcobalamin
This dietary supplement is free from dairy products, soy, sugar, gluten, and GMOs, as well as artificial sweeteners, colourings, preservatives, hydrogenated oils, corn syrup, and magnesium stearate. It comes in a dark glass jar that is free from BPA, phthalates, and other hormone-disrupting substances. The product is manufactured under HACCP standards in the EU and is suitable for both vegans and vegetarians.
| Content per daily dose (1 capsule) | % of RDI | |
|---|---|---|
| Vitamin B12 as methylcobalamin | 100 μg | 4000 |
RDI = Recommended Daily Intake
* RDI not established
Other ingredients
Vegetable capsule (hydroxypropylmethylcellulose).
Dosage
Take 1 capsule daily, preferably in the morning and ideally with a meal. If you have difficulty swallowing, the capsule can be opened, and the contents can be sprinkled onto food or into a drink that is consumed immediately.
Note
The recommended daily dose should not be exceeded. Keep out of reach of children. Food supplements should not be used as a substitute for a varied diet. A diverse and balanced diet, along with a healthy lifestyle, is important. Store in a dry and dark place at room temperature. Never place food supplements in direct sunlight, in a damp environment, or near a heat source. Consult your doctor before use if you are pregnant, breastfeeding, or have a medical condition. Store in a cool, dry place. Made in the EU. Seal the container properly.
What is vitamin B12 and why is it so important for the body?
Vitamin B12 is an essential nutrient that the body needs for several key functions, including the formation of red blood cells, energy metabolism, nervous system function, and DNA synthesis. Since the body cannot produce B12 on its own, it must be obtained through diet or supplements. B12 also plays an important role in combating fatigue and exhaustion, as it is involved in energy production in the mitochondria. A deficiency in vitamin B12 can lead to anemia (megaloblastic anemia), nerve damage, memory problems, concentration difficulties, and psychological symptoms such as depression and anxiety.
Who is at the greatest risk of vitamin B12 deficiency?
Vitamin B12 deficiency is particularly common among vegans and vegetarians, as B12 is exclusively found in animal products such as meat, fish, eggs, and dairy. Spirulina does not contain active vitamin B12, so it does not counteract B12 deficiency. Additionally, older adults, individuals with reduced stomach acid production (e.g., due to the use of proton pump inhibitors like Omeprazole), and those with gastrointestinal diseases such as celiac disease, Crohn's disease, or gastritis may have difficulty absorbing the vitamin. Pregnant and breastfeeding women may also have an increased need, as B12 is essential for the development of the nervous system and brain in the fetus and infant.
How does a deficiency in vitamin B12 manifest?
The symptoms of B12 deficiency can be vague at first but become clearer over time. Common signs include fatigue, dizziness, tingling or numbness in the hands and feet, pale skin, shortness of breath, difficulty concentrating, depression, and memory problems. Since B12 affects the myelin sheaths around the nerves, prolonged deficiency can also lead to neurological damage that is difficult to reverse. However, an early detected deficiency can quickly improve with the right supplementation.
What is the difference between methylcobalamin and cyanocobalamin?
Methylcobalamin is the active and natural form of vitamin B12, which the body can use directly in its biochemical processes. Cyanocobalamin is a synthetic form that must be converted to methylcobalamin and adenosylcobalamin before it becomes biologically active. Methylcobalamin therefore has higher bioavailability and effectiveness, and it is also gentler on the body as it does not contain cyanide groups like cyanocobalamin does. For individuals with impaired conversion ability (which may be due to genetic variations in the MTRR or MTHFR genes), methylcobalamin is therefore a significantly better choice.
What are the main functions of vitamin B12?
Vitamin B12 is essential for several processes in the body. It is needed for the production of red blood cells, which prevents anemia and improves oxygen transport in the body. It is also necessary for the function and repair of the nervous system, as it participates in the synthesis of myelin, the protective sheath around nerves. Additionally, B12 plays a key role in the methylation cycle, a biochemical process that affects DNA repair, detoxification, homocysteine levels, and the synthesis of neurotransmitters such as serotonin and dopamine. Therefore, B12 also has a significant impact on mood, cognitive function, and mental well-being.
Why is B12 important in combination with folate (B9)?
Vitamin B12 and folate (B9) work together in several biochemical processes, particularly in the synthesis of DNA and in the conversion of homocysteine to methionine. A deficiency in one can mask or worsen a deficiency in the other. Therefore, it is often recommended that B12 and folate be taken together, especially in cases of fatigue, fertility issues, or pregnancy, as they collectively support cell division, the nervous system, and energy production.
What does Vitamin B12 Methylcobalamin from Greatlife contain?
Each capsule contains 100 µg of vitamin B12 in the form of methylcobalamin, which corresponds to 4000% of the daily reference intake (DRI). The dosage is intended to ensure good levels even in individuals with impaired absorption or higher needs.
When and how should Vitamin B12 Methylcobalamin be taken?
It is recommended to take 1 capsule daily, preferably in the morning with a meal. Since B12 contributes to energy metabolism and can provide a slight stimulating effect for some individuals, it is best to avoid taking it late in the day. If there are difficulties swallowing, the capsule can be opened and the contents sprinkled on food or dissolved in a drink.
Who can particularly benefit from Vitamin B12 Methylcobalamin?
In addition to vegans, vegetarians, and older individuals, those experiencing fatigue, low blood values, poor concentration, depression, or tingling in the extremities may also benefit from extra B12. It is also a valuable supplement for individuals with genetic variations in methylation pathways (e.g., MTHFR or MTRR mutations), where the body's ability to utilize folate and B12 is impaired.
Can you take Vitamin B12 Methylcobalamin together with other supplements?
Yes, B12 works excellently together with folate (5-MTHF) and vitamin B6 (P5P), which together contribute to normal homocysteine metabolism. It is often combined with NRC for NAD+ or Magnesium M4 to optimize energy metabolism and nerve function.